| Rank | Expected Points Added (EPA) | Rusher | Team | Plays | EPA/Play | Success Rate |
|---|---|---|---|---|---|---|
| 12.940 | T.Allgeier | ATL | 0.090 | 0.455 | ||
| 10.610 | A.Dillon | GB | 0.096 | 0.482 | ||
| 5.063 | M.Sanders | PHI | 0.032 | 0.471 | ||
| 2.682 | C.McCaffrey | SF | 0.017 | 0.404 | ||
| 2.142 | T.Pollard | DAL | 0.017 | 0.372 | ||
| 2.062 | A.Ekeler | LAC | 0.017 | 0.451 | ||
| 0.057 | D.Foreman | CAR | 0.000 | 0.418 | ||
| -0.831 | C.Akers | LA | -0.006 | 0.428 | ||
| -3.167 | A.Jones | GB | -0.023 | 0.432 | ||
| -4.026 | I.Pacheco | KC | -0.030 | 0.493 | ||
| -7.199 | J.Conner | ARI | -0.054 | 0.425 | ||
| -7.536 | B.Robinson | WAS | -0.046 | 0.427 | ||
| -7.548 | L.Murray | DEN | -0.054 | 0.397 | ||
| -8.246 | N.Chubb | CLE | -0.046 | 0.406 | ||
| -9.320 | T.Etienne | JAX | -0.059 | 0.392 | ||
| -9.605 | D.Singletary | BUF | -0.079 | 0.410 | ||
| -11.891 | E.Elliott | DAL | -0.094 | 0.381 | ||
| -12.796 | S.Barkley | NYG | -0.083 | 0.348 | ||
| -13.884 | N.Harris | PIT | -0.079 | 0.434 | ||
| -15.023 | D.Montgomery | CHI | -0.116 | 0.364 | ||
| -15.409 | K.Walker | SEA | -0.095 | 0.344 | ||
| -18.199 | J.Taylor | IND | -0.177 | 0.350 | ||
| -18.503 | R.White | TB | -0.176 | 0.324 | ||
| -19.074 | D.Henry | TEN | -0.085 | 0.379 | ||
| -19.798 | Ja.Williams | DET | -0.116 | 0.427 | ||
| -23.440 | J.Jacobs | LV | -0.099 | 0.401 | ||
| -25.415 | R.Stevenson | NE | -0.217 | 0.376 | ||
| -26.185 | A.Kamara | NO | -0.177 | 0.351 | ||
| -27.925 | D.Pierce | HOU | -0.243 | 0.339 | ||
| -42.191 | D.Cook | MIN | -0.245 | 0.302 |